Gastrointestinal Disorders in Adolescents and Young Adults

Preparing for a Smooth Transition to Adult-Centered Care
Published:October 22, 2022DOI:


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        • Hyams J.S.
        • Di Lorenzo C.
        • Saps M.
        • et al.
        Childhood Functional Gastrointestinal Disorders: Child/Adolescent.
        Gastroenterology. 2016; 150: 1456-1468.e2
        • Rasquin A.
        • Di Lorenzo C.
        • Forbes D.
        • et al.
        Childhood Functional Gastrointestinal Disorders: Child/Adolescent.
        Gastroenterology. 2006; 130: 1527-1537
        • Maddux M.H.
        • Deacy A.D.
        • Colombo J.M.
        Organic Gastrointestinal Disorders.
        in: Carter B. Kullgren K. Clinical handbook of psychological consultation in pediatric medical settings. Springer Nature, 2020: 195-210
        • Lewis M.L.
        • Palsson O.S.
        • Whitehead W.E.
        • et al.
        Prevalence of Functional Gastrointestinal Disorders in Children and Adolescents.
        J Pediatr. 2016; 177: 39-43.e3
        • Abramson O.
        • Durant M.
        • Mow W.
        • et al.
        Incidence, Prevalence, and Time Trends of Pediatric Inflammatory Bowel Disease in Northern California, 1996 to 2006.
        J Pediatr. 2010; 157: 233-239.e1
        • Baldassano R.N.
        • Piccoli D.A.
        Inflammatory bowel disease in pediatric and adolescent patients.
        Gastroenterol Clin North Am. 1999; 28: 445-458
        • Rosen M.J.
        • Dhawan A.
        • Saeed S.A.
        Inflammatory Bowel Disease in Children and Adolescents.
        JAMA Pediatr. 2015; 169: 1053-1060
        • Carroll M.W.
        • Kuenzig M.E.
        • Mack D.R.
        • et al.
        The Impact of Inflammatory Bowel Disease in Canada 2018: Children and Adolescents with IBD.
        J Can Assoc Gastroenterol. 2019; 2: S49-S67
        • Greenley R.N.
        • Hommel K.A.
        • Nebel J.
        • et al.
        A Meta-analytic Review of the Psychosocial Adjustment of Youth with Inflammatory Bowel Disease.
        J Pediatr Psychol. 2010; 35: 857-869
        • Mackner L.M.
        • Greenley R.N.
        • Szigethy E.
        • et al.
        Psychosocial Issues in Pediatric Inflammatory Bowel Disease: Report of the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition.
        J Pediatr Gastroenterol Nutr. 2013; 56: 449-458
        • Mackner L.M.
        • Bickmeier R.M.
        • Crandall W.V.
        Academic Achievement, Attendance, and School-Related Quality of Life in Pediatric Inflammatory Bowel Disease.
        J Dev Behav Pediatr. 2012; 33: 106-111
        • Engström I.
        Mental health and psychological functioning in children and adolescents with inflammatory bowel disease: a comparison with children having other chronic illnesses and with healthy children.
        J Child Psychol Psychiatry. 1992; 33: 563-582
        • Ross S.C.
        • Strachan J.
        • Russell R.K.
        • et al.
        Psychosocial Functioning and Health-related Quality of Life in Paediatric Inflammatory Bowel Disease.
        J Pediatr Gastroenterol Nutr. 2011; 53: 480-488
        • Robins P.M.
        • Smith S.M.
        • Glutting J.J.
        • et al.
        A Randomized Controlled Trial of a Cognitive-Behavioral Family Intervention for Pediatric Recurrent Abdominal Pain.
        J Pediatr Psychol. 2005; 30: 397-408
        • Whitehead W.E.
        • Palsson O.
        • Jones K.R.
        Systematic review of the comorbidity of irritable bowel syndrome with other disorders: What are the causes and implications?.
        Gastroenterology. 2002; 122: 1140-1156
        • Chitkara D.K.
        • van Tilburg M.A.L.
        • Blois-Martin N.
        • et al.
        Early life risk factors that contribute to irritable bowel syndrome in adults: a systematic review.
        Am J Gastroenterol. 2008; 103
        • Hardin A.P.
        • Hackell J.M.
        Age Limit of Pediatrics.
        Pediatrics. 2017; 140: e20172151
        • Nardone O.M.
        • Iacucci M.
        • Ghosh S.
        • et al.
        Can a transition clinic bridge the gap between paediatric and adult inflammatory bowel disease care models?.
        Dig Liver Dis. 2020; 52: 516-527
        • Arnett J.J.
        Conceptions of the Transition to Adulthood: Perspectives From Adolescence Through Midlife.
        J Adult Development. 2001; 8: 133-143
        • Arnett J.J.
        Emerging Adulthood: Understanding the New Way of Coming of Age.
        in: Arnett J. Tanner J. Emerging adults in America: coming of age in the 21st century. American Psychological Association, 2006: 3-19
        • Benson J.E.
        • Elder G.H.
        Young Adult Identities and Their Pathways: A Developmental and Life Course Model.
        Dev Psychol. 2011; 47: 1646-1657
        • Alazri M.
        • Heywood P.
        • Neal R.D.
        • et al.
        Continuity of Care.
        Sultan Qaboos Univ Med J. 2007; 7: 197-206
        • Blum R.W.M.
        • Garell D.
        • Hodgman C.H.
        • et al.
        Transition from child-centered to adult health-care systems for adolescents with chronic conditions: A position paper of the Society for Adolescent Medicine.
        J Adolesc Health. 1993; 14: 570-576
        • Bert F.
        • Camussi E.
        • Gili R.
        • et al.
        Transitional care: A new model of care from young age to adulthood.
        Health Policy. 2020; 124: 1121-1128
        • Stollon N.
        • Zhong Y.
        • Ferris M.
        • et al.
        Chronological age when health care transition skills are mastered in adolescents/young adults with inflammatory bowel disease.
        World J Gastroenterol. 2017; 23: 3349-3355
        • Lotstein D.S.
        • Inkelas M.
        • Hays R.D.
        • et al.
        Access to Care for Youth with Special Health Care Needs in the Transition to Adulthood.
        J Adolesc Health. 2008; 43: 23-29
        • Cooley W.C.
        • Sagerman P.J.
        • American Academy of Pediatrics AA of F.P.
        Supporting the Health Care Transition From Adolescence to Adulthood in the Medical Home.
        Pediatrics. 2011; 128: 182-200
        • Philpott J.R.
        • Kurowski J.A.
        Challenges in Transitional Care in Inflammatory Bowel Disease: A Review of the Current Literature in Transition Readiness and Outcomes.
        Inflamm Bowel Dis. 2019; 25: 45-55
        • Annunziato R.A.
        • Emre S.
        • Shneider B.
        • et al.
        Adherence and medical outcomes in pediatric liver transplant recipients who transition to adult services.
        Pediatr Transplant. 2007; 11: 608-614
        • Cadario F.
        • Prodam F.
        • Bellone S.
        • et al.
        Transition process of patients with type 1 diabetes (T1DM) from paediatric to the adult health care service: a hospital-based approach.
        Clin Endocrinol. 2009; 71: 346-350
        • Zhao X.
        • Bjerre L.M.
        • Nguyen G.C.
        • et al.
        Health Services Use during Transition from Pediatric to Adult Care for Inflammatory Bowel Disease: A Population-Based Study Using Health Administrative Data.
        J Pediatr. 2018; 203: 280-287.e4
        • Stinson J.N.
        • Stevens B.J.
        • Feldman B.M.
        • et al.
        Construct validity of a multidimensional electronic pain diary for adolescents with arthritis.
        Pain. 2008; 136: 281-292
        • Gray W.N.
        • Holbrook E.
        • Morgan P.J.
        • et al.
        Transition Readiness Skills Acquisition in Adolescents and Young Adults with Inflammatory Bowel Disease: Findings from Integrating Assessment into Clinical Practice.
        Inflamm Bowel Dis. 2015; 21: 1125-1131
        • Benchimol E.I.
        • Walters T.D.
        • Kaufman M.
        • et al.
        Assessment of knowledge in adolescents with inflammatory bowel disease using a novel transition tool.
        Inflamm Bowel Dis. 2011; 17: 1131-1137
        • Fishman L.N.
        • Barendse R.M.
        • Hait E.
        • et al.
        Self-Management of Older Adolescents with Inflammatory Bowel Disease: A Pilot Study of Behavior and Knowledge as Prelude to Transition.
        Clin Pediatr (Phila). 2010; 49: 1129-1133
        • Sebastian S.
        • Jenkins H.
        • McCartney S.
        • et al.
        The requirements and barriers to successful transition of adolescents with inflammatory bowel disease: Differing perceptions from a survey of adult and paediatric gastroenterologists.
        J Crohn’s Colitis. 2012; 6: 830-844
        • Elli L.
        • Maieron R.
        • Martelossi S.
        • et al.
        Transition of gastroenterological patients from paediatric to adult care: A position statement by the Italian Societies of Gastroenterology.
        Dig Liver Dis. 2015; 47: 734-740
        • Eluri S.
        • Book W.M.
        • Kodroff E.
        • et al.
        Lack of Knowledge and Low Readiness for Health care Transition in Eosinophilic Esophagitis and Eosinophilic Gastroenteritis.
        J Pediatr Gastroenterol Nutr. 2017; 65: 53-57
        • Gray W.N.
        • Maddux M.H.
        Current Transition Practices in Pediatric IBD: Findings from a National Survey of Pediatric Providers.
        Inflamm Bowel Dis. 2016; 22: 372-379
        • Jawaid N.
        • Jeyalingam T.
        • Nguyen G.
        • et al.
        Paediatric to Adult Transition of Care in IBD: Understanding the Current Standard of Care Among Canadian Adult Academic Gastroenterologists.
        J Can Assoc Gastroenterol. 2020; 3: 266-273
        • Ballou S.
        • Keefer L.
        Psychological Interventions for Irritable Bowel Syndrome and Inflammatory Bowel Diseases.
        Clin Translational Gastroenterol. 2017; 8: e214
        • Dovey T.
        A biopsychosocial framework to understand children and young people with gastrointestinal problems.
        in: Martin C. Dovey T. Paediatric gastrointestinal disorders. CRC Press, London, UK2014
        • Bradford A.
        Introduction to the Special Issue: Advances in Psychogastroenterology.
        J Clin Psychol Med Settings. 2020; 27: 429-431
        • Keefer L.
        • Palsson O.S.
        • Pandolfino J.S.
        Best Practice Update: Incorporating Psychogastroenterology Into Management of Digestive Disorders.
        Gastroenterology. 2018; 154: 1249-1257
        • van Tilburg M.A.L.
        Psychogastroenterology: A Cure, Band-Aid, or Prevention?.
        Children. 2020; 7: 121
        • Schurman J.V.
        • Friesen C.A.
        Integrative treatment approaches: family satisfaction with a multidisciplinary paediatric Abdominal Pain Clinic.
        Int J Integr Care. 2010; 10: e51
        • Varty M.
        • Popejoy L.L.
        A Systematic Review of Transition Readiness in Youth with Chronic Disease.
        West J Nurs Res. 2020; 42: 554-566
        • Colver A.
        • Longwell S.
        New understanding of adolescent brain development: relevance to transitional health care for young people with long term conditions.
        Arch Dis Child. 2013; 98: 902-907
        • Leung Y.
        • Heyman M.
        • Mahadevan U.
        Transitioning the Adolescent Inflammatory Bowel Disease Patient: Guidelines for the Adult and Pediatric Gastroenterologist.
        Inflamm Bowel Dis. 2011; 17: 2169-2173
        • Levy R.L.
        • Whitehead W.E.
        • Walker L.S.
        • et al.
        Increased Somatic Complaints and Health-Care Utilization in Children: Effects of Parent IBS Status and Parent Response to Gastrointestinal Symptoms.
        Official J Am Coll Gastroenterol ACG. 2004; 99: 2442-2451
        • Peterson C.C.
        • Palermo T.M.
        Parental Reinforcement of Recurrent Pain: The Moderating Impact of Child Depression and Anxiety on Functional Disability.
        J Pediatr Psychol. 2004; 29: 331-341
        • Reed-Knight B.
        • Blount R.L.
        • Gilleland J.
        The transition of health care responsibility from parents to youth diagnosed with chronic illness: A developmental systems perspective.
        Fam Syst Health. 2014; 32: 219
        • Laursen B.
        • Hartl A.C.
        Understanding loneliness during adolescence: Developmental changes that increase the risk of perceived social isolation.
        J Adolescence. 2013; 36: 1261-1268
        • Cole R.
        • Ashok D.
        • Razack A.
        • et al.
        Evaluation of Outcomes in Adolescent Inflammatory Bowel Disease Patients Following Transfer From Pediatric to Adult Health Care Services: Case for Transition.
        J Adolesc Health. 2015; 57: 212-217
        • Colver A.
        • McConachie H.
        • Le Couteur A.
        • et al.
        A longitudinal, observational study of the features of transitional health care associated with better outcomes for young people with long-term conditions.
        BMC Med. 2018; 16: 111
        • Schütz L.
        • Radke M.
        • Menzel S.
        • et al.
        Long-term implications of structured transition of adolescents with inflammatory bowel disease into adult health care: a retrospective study.
        BMC Gastroenterol. 2019; 19: 128
        • Canadian Association of Pediatric Health Centres (CAPHC)
        A guideline for transition from Paediatric to adult health care for youth with special health care needs: a national approach.
        2016 (Available at:) (Accessed November 20, 2021)
        • Pinzon J.L.
        • Jacobson K.
        • Reiss J.
        Say Goodbye and Say Hello: The Transition from Pediatric to Adult Gastroenterology.
        Can J Gastroenterol. 2004; 18: 735-742
        • Paone M.C.
        • Wigle M.
        • Saewyc E.
        The ON TRAC Model for Transitional Care of Adolescents.
        Prog Transplant. 2006; 16: 291-302
        • Mulvale G.
        • Nguyen T.
        • Miatello A.
        • et al.
        Lost in transition or translation? Care philosophies and transitions between child and youth and adult mental health services: a systematic review.
        J Ment Health (Abingdon, England). 2016; 28: 1-10