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Contributors
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iii-v
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Contents
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vii-xi
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Forthcoming Issues
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xii
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Evaluation of Inflammatory Bowel Disease
16 February 2012
The diagnosis and management of inflammatory bowel disease (IBD) is often complex. Better techniques for assessing IBD are needed. In this issue of Gastroenterology Clinics of North America, we focus ...
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Samir A. Shah,
Adam Harris,
Edward Feller
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xiii-xiv
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| Endoscopy and capsule endoscopy |
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Endoscopic Assessment of Inflammatory Bowel Disease: Colonoscopy/Esophagogastroduodenoscopy
Endoscopy plays an essential role in the diagnosis, management, and surveillance of inflammatory bowel disease (IBD). Endoscopy in combination with clinical findings, blood tests, and stool analysis c...
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Grace Chan,
David S. Fefferman,
Richard J. Farrell
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271-290
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Chromoendoscopy in Inflammatory Bowel Disease
Patients with longstanding, extensive ulcerative colitis are at increased risk of developing colorectal cancer. The risk is lower than previously reported, but colonoscopic surveillance is recommended...
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Ralf Kiesslich,
Markus F. Neurath
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291-302
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Evaluation for Postoperative Recurrence of Crohn Disease
Crohn disease is a chronic inflammatory condition, affecting the entire gastrointestinal tract, that follows a relapsing and remitting course. Approximately two-thirds of patients with Crohn disease u...
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Jason M. Swoger,
Miguel Regueiro
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303-314
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The Role of Capsule Endoscopy in Evaluating Inflammatory Bowel Disease
16 February 2012
Inflammatory bowel disease (IBD) is a generic term used to describe Crohn disease (CD), ulcerative colitis (UC) or IBD type unclassified (IBDU), formerly known as indeterminate colitis. By definition,...
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Silvio W. de Melo,
Jack A. Di Palma
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315-323
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| Special situations |
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Health Maintenance in the Inflammatory Bowel Disease Patient
27 February 2012
Recent data suggest that inflammatory bowel disease (IBD) patients do not receive preventive services with the same rigor as other medical patients, partly because their gastroenterologist is often th...
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Jennifer A. Sinclair,
Sharmeel K. Wasan,
Francis A. Farraye
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325-337
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Detecting and Treating Clostridium Difficile Infections in Patients with Inflammatory Bowel Disease
16 February 2012
Clostridium difficile is a Gram-positive anaerobe described as early as 1935 as being a member of the intestinal flora in neonates. It was not until 1978 that it was first described in association wit...
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Ashwin N. Ananthakrishnan
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339-353
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Evaluating Pouch Problems
Approximately 20% to 30% of patients with ulcerative colitis (UC) eventually require surgery for failure of medical therapy or development of neoplasia. Restorative proctocolectomy with ileal pouch-an...
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Yue Li,
Bo Shen
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355-378
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The Evaluation and Treatment of Crohn Perianal Fistulae: EUA, EUS, MRI, and Other Imaging Modalities
27 February 2012
Perianal fistula, defined as an abnormal communication between the anal canal or lower rectum and the perianal or perineal skin, is among the more morbid manifestations of Crohn disease (CD). The deve...
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Paul E. Wise,
David A. Schwartz
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379-391
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Optimizing Immunomodulators and Anti-TNF Agents in the Therapy of Crohn Disease
Randomized controlled trials support the use of the thiopurines and anti-tumor necrosis factor α (anti-TNF) monoclonal antibodies (mAb's) in the treatment of Crohn disease (CD). Nonetheless, lack of r...
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Themistocles Dassopoulos,
Charles A. Sninsky
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393-409
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Patient-Specific Approach to Combination Versus Monotherapy with the Use of Antitumor Necrosis Factor α Agents for Inflammatory Bowel Disease
16 February 2012
There is little debate that monoclonal antibodies directed against tumor necrosis factor-α (anti-TNFα) represent important tools in our armamentarium in the management of inflammatory bowel disease (I...
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Shane M. Devlin,
Adam S. Cheifetz,
Corey A. Siegel,
BRIDGe group
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411-428
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Disability in Inflammatory Bowel Disease
It is surprising how little is known about disability in patients with inflammatory bowel disease (IBD). There are sparse data on IBD-related disability compared with other chronic inflammatory diseas...
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Bincy P. Abraham,
Joseph H. Sellin
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429-441
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| Noninvasive evaluation |
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Clinical Predictors of Aggressive/Disabling Disease: Ulcerative Colitis and Crohn Disease
Inflammatory bowel disease (IBD) is classically characterized by periods of remission and clinical relapse. In some patients disease may take an aggressive course that involves frequent relapses, cont...
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Wojciech Blonski,
Anna M. Buchner,
Gary R. Lichtenstein
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443-462
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The Promise and Pitfalls of Serologic Testing in Inflammatory Bowel Disease
Serologies have well-established roles in the diagnosis of a variety of immunologically driven diseases; rheumatologists rely on an alphabet soup of antibodies, hepatologists depend on serologic tests...
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Joseph H. Sellin,
Rajesh R. Shah
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463-482
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Fecal Markers: Calprotectin and Lactoferrin
20 February 2012
Differentiating patients with inflammatory disease from those with functional disorders may be difficult in patients with nonspecific symptoms, such as diarrhea and abdominal pain. Most often, invasiv...
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Bincy P. Abraham,
Sunanda Kane
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483-495
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Imaging for Luminal Disease and Complications: CT Enterography, MR Enterography, Small-Bowel Follow-Through, and Ultrasound
In the past decade, there has been a seismic shift in the use of imaging for Crohn disease (CD) away from small-bowel follow-through (SBFT) to cross-sectional techniques, most commonly computed tomogr...
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David J. Grand,
Adam Harris,
Edward V. Loftus
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497-512
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Genetics in Diagnosing and Managing Inflammatory Bowel Disease
27 February 2012
Although inflammatory bowel disease (IBD) is found worldwide, the majority of studies have focused on white populations in North America and Europe. The incidence (or number of new cases per year) and...
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Jacob L. McCauley,
Maria T. Abreu
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513-522
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Index
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523-537
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